|
Document Type |
: |
Thesis |
|
Document Title |
: |
Effect of Moringa and Neem Ethanolic Leaves Extract on Blood Glucose Level in Male Diabetic Rats تأثير المستخلص الكحولي لأوراق المورنجا والنيم على مستويات السكر في الدم لدى ذكور الفئران المصابة بالسكري |
|
Subject |
: |
Faculty of Home Economics |
|
Document Language |
: |
Arabic |
|
Abstract |
: |
The study was conducted to evaluate the effect of moringa, neem ethanolic leaves extract and their combination on blood glucose level in diabetic male rats. Male albino rats (n=56)weighing(200-250 g)were divided into2 main groups;first:negative control(n=8)fed standard diet. second:diabetic rats(n=48),which divided equally to 6 subgroups as follows:G1:diabetic untreated rats(positive control),G2andG3 diabetic rats were treated with moringa(250 and 500 mg/kg b.wt/day) respectively,G4andG5diabetic rats were treated with neem(250and500mg/kg b.wt/day)respectively andG6diabetic rats were treated with(moringa and neem combined extracts250mg/kg b.wt/day of each). Diabetes was induced by a single intraperitonial injection of STZ(40mg/kg body weight).The STZ-induced diabetic group exhibited very highly significant(p<0.05)hyperglycemia,hyperlipidemia,with weight loss when compared with control negative group.Treatment with moringa,neem or their mixture reported very highly significant(p<0.05)improvement in all parameters when compared with untreated diabetic group.Histopathological investigation of liver and pancreatic tissues of diabetic rats represented the presence of sever changes, meanwhile treatment overcome this changes,the majority of the cells tend to be normal. The study demonstrated that the combination of both moringa and neem improve the serum glucose,insulin levels,lipid profile and histopathological changes of liver and pancreas in diabetic rats. Key words:Moringa,Neem,glucose level,insulin level |
|
Supervisor |
: |
Dr. Reham Abo Elmahasen Arafat |
|
Thesis Type |
: |
Master Thesis |
|
Publishing Year |
: |
1438 AH
2017 AD |
|
Added Date |
: |
Thursday, January 19, 2017 |
|
Researchers
| المـهـا نـوار البقمي | Albogami, Almaha Nawar | Researcher | Master | |
|