Document Details

Document Type : Thesis 
Document Title :
“EFFECT OF VITAMIN D AND CALCIUM SUPPLEMENTATIONS ON REDUCING THE INCIDENCE OF HYPOCALCEMIA AFTER THYROIDECTOMY”
"تأثير فيتامين د ومكملات الكالسيوم على تقليل حدوث نقص الكالسيوم في الدم بعد استئصال الغدة الدرقية"
 
Subject : Faculty of Home Economics 
Document Language : Arabic 
Abstract : Hypocalcemia is a frequent complication after total thyroidectomy. The objectives of thesis work are to evaluate the potential role of routine calcium or vitamin D supplementation for the prevention of post-thyroidectomy hypocalcemia and to draw therapy guidelines that may prevent this common complication. Methods: A prospective study was carried out from March 2016 to May 2017. Thirty consecutive patients who underwent total or hemi-thyroidectomy were included in the study. They were received oral calcium carbonate (1300 mg/day) and Vitamin D3 (600 IU/day) post-operative surgery, Symptoms and signs of hypocalcemia were monitored. The level of vitamin D3, calcium and other biomedical variables were measured pre and postoperatively at 24h, 48h, 30 day and 90 day after thyroidectomy and compared statistically by a t-test, Chi-Square test and Mann-Whitney U test. Serum calcium level <2 mmol /L was considered as laboratory hypocalcemia. Results: The rates of hypocalcemia symptoms were 50%. In comparison to preoperative, vitamin D3 and parathyroid hormone levels were increased significantly in postoperative follow-up (30 d and 90 d after thyroidectomy). Calcium and albumin levels were increased significantly in postoperative (90 d after thyroidectomy). Calcium level was above the level of laboratory hypocalcemia throughout preoperative and postoperative follow-up. on the other side, thyroid-stimulating hormone (TSH), triiodothyronine and thyroglobulin were decreased significantly in postoperative (30 d after thyroidectomy), postoperative (90 d after thyroidectomy), postoperative (30 d and 90 d after thyroidectomy), respectively. TSH was in the Laboratory Reference Values in preoperative and postoperative follow-up. Conclusion: Routine post-thyroidectomy calcium and Vitamin D3 supplementation can significantly reduce postoperative hypocalcemia. Keywords: Vitamin D- Hypocalcemia – Thyroidectomy- Calcium Supplementations. 
Supervisor : Dr. Fatimah Mohammed Ali Yousef 
Thesis Type : Master Thesis 
Publishing Year : 1439 AH
2018 AD 
Co-Supervisor : Dr. Hani Zohir Marzouki 
Added Date : Tuesday, July 10, 2018 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
هبه منصور الصبحيAlsubhi, Heba MansourResearcherMaster 

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